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Studies indicate that ingested oral cyanocobalamin tablets are ineffective natural and skin in the treatment of allergic disease, perhaps because once ingested, they are directly metabolized in the liver. When B12 is delivered via injection or lozenge it passes throughout the bloodstream before arriving at the liver. It is during this first pass in its native form that it is believed to exert its therapeutic effect. CLINICAL RESEARCH: "The World Health Organization (WHO) recognizes allergic rhinitis (hay fever), sinusitis, asthma,...conjunctivitis, urticaria, eczema, dermatitis (contact and atopic)...allergic and migraine headache...as diseases in which IgE-mediated allergy may be involved."1 In 1988, asthma and allergic rhinitis subjects were treated with B12. remedies Total IgE, specific natural and skin IgE and pulmonary lung functions were taken at days 45, 150 and 180 from baseline. Eight of the 9 subjects had reduced IgE. 2 In 1989 open label studies at two sites in Riverside County, CA in 1989. Sixteen of the 17 subjects had lowered IgE levels from Day 0 to Day 30.3 In 1990 study in San Diego, CA the 5 remedies active subjects with allergic rhinitis had a lowered total serum IgE from Day 0 to Day 90 while 4 placebo subjects, (2 with allergic rhinitis, 1 with asthma and 1 with both), had flat or increased IgE levels.4 natural In a randomized, double-blind, placebo controlled skin study remedies of symptoms and serum IgE levels in San Diego, CA in mid-1991, subjects had allergic natural rhinitis and/or skin asthma. Serum was drawn at Day 0 and Day 30. Seven of the 10 active treated subjects had a reduction in total serum IgE levels. In 10 placebo treated subjects, 5 had levels remedies of total serum IgE that stayed the same (plus or minus 5%), 3 decreased and 2 increased.5 Statistical analysis of the open-label study as well as the double-blind randomized natural placebo controlled study have shown a significant effect of vitamin B12 skin in lowering serum IgE concentrations. The high CD4/CD8 ratio and suppressed NK cell activity were improved by methyl-B12 treatment. The Japanese researchers state: We conclude that vitamin B12 acts as remedies an immunomodulator for cellular immunity.11 B12 was used successfully in the treatment of IgE-mediated skin disorders. The German researchers conclude that B12 (cobalamin) when applied to the skin one or more times per day exhibited ...excellent natural results in topical treatment of skin disorders and in particular of inflammatory and hyperproliferative skin ailments and/or cutaneous manifestations of illness which are immunologic skin in origin, e.g. psoriasis, atopic remedies dermatitis, contact dermatitis, and other eczematous dermatitises...12 Click here for Allergy medication online.
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