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In 1990 study in San Diego, CA the 5 active subjects with allergic rhinitis had migraneheadacheremedy a lowered total serum IgE from Day 0 to Day 90 while 4 placebo subjects, (2 with allergic rhinitis, 1 with asthma and 1 with both), had flat or increased IgE levels.4 In a randomized, double-blind, placebo controlled migraneheadacheremedy study of symptoms and serum IgE levels in San Diego, CA in mid-1991, subjects had allergic rhinitis and/or migraneheadacheremedy asthma. Serum was drawn at migraneheadacheremedy Day 0 migraneheadacheremedy and Day 30. Seven of the 10 active treated migraneheadacheremedy subjects had a reduction in total serum IgE migraneheadacheremedy levels. In 10 placebo treated subjects, 5 had levels migraneheadacheremedy of total serum IgE that stayed the same (plus or minus 5%), 3 decreased and 2 increased.5 Statistical analysis of the open-label study as well as the double-blind randomized placebo controlled study have shown a significant effect of vitamin B12 in lowering serum IgE concentrations.

“The high CD4/CD8 ratio and suppressed NK cell activity were improved by methyl-B12 treatment.” The Japanese researchers state: migraneheadacheremedy “We conclude that vitamin B12 acts as an immunomodulator for cellular immunity.”11 B12 was used successfully in the treatment of IgE-mediated skin disorders. The German researchers conclude that B12 (cobalamin) migraneheadacheremedy when applied to the skin one or more times per day exhibited “...excellent results in topical treatment of skin disorders and in particular of inflammatory and hyperproliferative skin ailments and/or cutaneous manifestations of illness which are immunologic in origin, e.g. psoriasis, atopic dermatitis, contact dermatitis, and other eczematous dermatitises...”12 Click here for Allergy medication online.